Heather M. Stapleton

Enduring Autism-like Phenotypes and Deregulated Hypothalamic Prosocial Peptides After Early-Life Exposure to Indoor Flame Retardants in Male C57BL/6 Mice

This study shows that early-life exposure to PBDEs in mice leads to autism-like behaviors and changes in prosocial neuropeptide expression.

Developmental PBDE exposure impairs histamine release from mast cells by altering granule maturation and calcium signaling in adult male and female mice

This study shows developmental PBDE exposure impairs mast cell function in adult mice by disrupting granule maturation and calcium signaling, leading to reduced histamine release.

Structure-specific variation in per- and polyfluoroalkyl substances toxicity among genetically diverse Caenorhabditis elegans strains

The paper assesses PFAS toxicity across genetically diverse C. elegans strains, finding genetic variation influences susceptibility to specific PFAS structures.

Persistent autism-relevant phenotype produced by in utero and lactational exposure of female mice to the commercial PBDE mixture, DE-71

This study shows that exposure to PBDE mixture DE-71 during pregnancy and lactation in female mice leads to autism-relevant behavioral and neurochemical changes in offspring.