Loss of TMEM55B modulates lipid metabolism through dysregulated lipophagy and mitochondrial function
Yuanyuan Qin, Sheila S. Teker, Nilsa La Cunza, Yao Tong, Elizabeth Theusch, Neil Victor Yang, Leela Venkatesan, Julia Su, Xuanwen Wang, Ronald M. Krauss, Aparna Lakkaraju, Aras N. Mattis, Marisa Wong Medina
This study shows that TMEM55B loss disrupts lipid metabolism by altering lipophagy and mitochondrial function, worsening MASLD in mice.
Cell Death and Disease · Jan 9, 2026Peer-reviewedCell Biology