Author

Göknur Kara

Houston MethodistORCID 0000-0002-5905-9758Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1 Assay:CRISPR screen· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Morgan HolcombiD· 4 shared Sonia VillapoliD· 4 shared Hannah FlinniD· 3 shared Austin MarshalliD· 2 shared Marissa BurkeiD· 2 shared Peter Park· 2 shared Anjana TiwariiD· 1 shared Biana GodiniD· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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4 shared papersNeuroscience

Morgan HolcombORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Intranasal CRISPR- lipid nanoparticles targeting MAPK9 reduce neuroinflammation after traumatic brain injury

Göknur Kara, Yaqoob Ali, Jessica López Espinosa, Peter Park, Morgan Holcomb, Hannah Flinn, Noah Taylor, Tyler Galbraith, Fransisca Leonard, Sonia Villapol

This paper develops an intranasal CRISPR-based therapy targeting MAPK9 in microglia to reduce neuroinflammation after traumatic brain injury, showing reduced inflammation and no toxicity.

bioRxiv · Apr 26, 2026 · PreprintNeuroscience

Simulated spaceflight disrupts the immune-gut-brain axis and drives sex-dependent neuroinflammation, axonal injury, and behavioral deficits.

Marissa Burke, Göknur Kara, Morgan Holcomb, Christopher E. Mason, Sonia Villapol

This study shows that simulated spaceflight stressors disrupt the immune-gut-brain axis, causing sex-dependent neuroinflammation, axonal injury, and behavioral issues in mice.

bioRxiv · Apr 13, 2026 · PreprintNeuroscience

Telomerase mRNA-Lipid nanoparticles attenuate neuroinflammation after traumatic brain injury in mice

Göknur Kara, Morgan Holcomb, Anjana Tiwari, Hannah Flinn, Trinity Eimer, Austin Marshall, Marissa Burke, Peter Park, Karem A. Court, John P. Cooke, Biana Godin, Sonia Villapol

This paper shows that delivering telomerase mRNA via lipid nanoparticles reduces neuroinflammation and oxidative stress after traumatic brain injury in mice.

Neurotherapeutics · Apr 1, 2026Peer-reviewedNeuroscience

Sex-specific effects of fecal microbiota transplantation on TBI-exacerbated Alzheimer's pathology in mice

Sirena Soriano, Austin Marshall, Morgan Holcomb, Hannah Flinn, M Burke, Göknur Kara, Paula Luciana Scalzo, Sonia Villapol

This study investigates how fecal microbiota transplantation (FMT) affects Alzheimer's pathology and neuroinflammation in male and female mice with traumatic brain injury, finding sex-specific outcomes.

bioRxiv · Sep 11, 2025 · PreprintNeuroscience