Author

Yatendra Kumar

MRC Human Genetics Unit, Institute of Genetics and Cancer, University of EdinburghPrimary ORCID profile (0000-0001-8371-2887 · 7 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Yatendra KumariD7 papers · Institute of Genetics and Cancer

Biology Disciplines

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Cell Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Andrea QuintanillaiD· 1 shared Bethany M BartlettiD· 1 shared Charlene BoumendiliD· 1 shared Juan Carlos AcostaiD· 1 shared Martin S Taylor· 1 shared Robert S Young· 1 shared Shelagh Boyle· 1 shared Tamoghna ChowdhuryiD· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

Andrea QuintanillaORCID

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2 papers

Recent·Most cited

TPR is required for cytoplasmic chromatin fragment formation during senescence

Bethany M Bartlett, Yatendra Kumar, Shelagh Boyle, Tamoghna Chowdhury, Andrea Quintanilla, Charlene Boumendil, Juan Carlos Acosta, Wendy A Bickmore

The paper shows TPR is required for early NF-κB activation during oncogene-induced senescence, leading to cytoplasmic chromatin fragment formation and SASP activation.

bioRxiv · Apr 18, 2024Cell Biology

Bidirectional transcription marks accessible chromatin and is not specific to enhancers

Robert S Young, Yatendra Kumar, Wendy A Bickmore, Martin S Taylor

The paper shows bidirectional transcription is common across all accessible chromatin regions, not just enhancers, and is not a reliable marker for enhancer activity.

Genome Biology · Dec 28, 2017Peer-reviewedGenomics