PIP2-Tmie Interactions Drive Mammalian Hair Cell Slow Adaptation Independently of Myosin Motors
Giusy A. Caprara, Sujin Jun, Ye-Ri Kim, Gabriel J. Olguín-Orellana, Yein Christina Park, Claudia Martínez-García, Sihan Li, Ángela Ballesteros, David Ramírez, Un‐Kyung Kim, Jung‐Bum Shin, Anthony W. Peng
This study shows that PIP2-Tmie interactions, not myosin motors, drive slow adaptation in mammalian hair cells, as demonstrated by rescue experiments and disruption studies.
bioRxiv · Apr 1, 2025 · PreprintBiophysics