Anthony W. Peng

Tonotopic Specialization of MYO7A Isoforms in Auditory Hair Cells

The paper identifies a novel MYO7A isoform, MYO7A-N, and shows its distinct expression and function in outer hair cells, contributing to hearing sensitivity and cochlear frequency resolution.

A Regulatory Axis for Tonotopic MYO7A Expression in Cochlear Hair Cells

The paper identifies a cis-regulatory element, EnhancerA, and the transcription factor SIX2 that regulate tonotopic Myo7a isoform expression in cochlear hair cells, linking cochlear position to protein diversity and function.

PIP2-Tmie Interactions Drive Mammalian Hair Cell Slow Adaptation Independently of Myosin Motors

This study shows that PIP2-Tmie interactions, not myosin motors, drive slow adaptation in mammalian hair cells, as demonstrated by rescue experiments and disruption studies.