Yein Christina Park

MARTINI 2.2 simulations show lateral tension changes the free energies of membrane bending and thickness deformations through a projected-area term (γΔΔA), while leaving lipid mixing, residence and exchange essentially unchanged.

This study identifies TMC1 and TMC2 as cholesterol-dependent lipid scramblases that regulate membrane homeostasis in auditory hair cells, linking their dysfunction to hereditary deafness.

This study shows that PIP2-Tmie interactions, not myosin motors, drive slow adaptation in mammalian hair cells, as demonstrated by rescue experiments and disruption studies.