Understanding the future risk of bat coronavirus spillover into humans: correlating sarbecovirus receptor usage, host range, and antigenicity.
Nazia Thakur, Joseph Newman, Dongchun Ni, Jeffrey Seow, Abigail L. Hay, Yeonjae Lee, Ayush Upadhyay, Babatunde Ekundayo, John A. Hammond, Thomas P. Peacock, Kelvin Lau, Katie J. Doores, Dalan Bailey
This study examines the host range and antigenicity of bat sarbecoviruses, finding that generalist ACE2 users are more related to SARS-CoV-2 and show broader cross-neutralization.
bioRxiv · Sep 3, 2025 · PreprintMicrobiology