Author

Kelvin Lau

École Polytechnique Fédérale de LausanneORCID 0000-0002-0700-7382Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein design· 1 Assay:protein structure· 1 Assay:proteomics· 1 Approach:simulation· 1 Approach:statistical model· 1

Frequent Co-Authors

Abigail L. HayiD· 1 shared Alberto BorsattoiD· 1 shared Alisa KhramushiniD· 1 shared Ayush UpadhyayiD· 1 shared Babatunde EkundayoiD· 1 shared Bruno E. CorreiaiD· 1 shared Christian SchellhaasiD· 1 shared Dalan BaileyiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMicrobiology

Abigail L. HayORCID

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Author profile →

2 papers

Recent·Most cited

Computational design of protein conformational landscapes for metamorphic behavior

Alisa Khramushin, Maddalena Elia, Christian Schellhaas, Alberto Borsatto, Joseph H. Schmidt, Mohamad Yazan Chabaan, Roberta Pierattelli, Kelvin Lau, Francesco Luigi Gervasio, Luciano A. Abriata, Bruno E. Correia

This study designs metamorphic proteins that switch between multiple conformations and shows how mutations can shift their conformational equilibrium.

bioRxiv · Oct 13, 2026 · PreprintSynthetic Biology

Understanding the future risk of bat coronavirus spillover into humans: correlating sarbecovirus receptor usage, host range, and antigenicity.

Nazia Thakur, Joseph Newman, Dongchun Ni, Jeffrey Seow, Abigail L. Hay, Yeonjae Lee, Ayush Upadhyay, Babatunde Ekundayo, John A. Hammond, Thomas P. Peacock, Kelvin Lau, Katie J. Doores, Dalan Bailey

This study examines the host range and antigenicity of bat sarbecoviruses, finding that generalist ACE2 users are more related to SARS-CoV-2 and show broader cross-neutralization.

bioRxiv · Sep 3, 2025 · PreprintMicrobiology