Joseph Newman

This study shows that presenting VP4 peptides in a virus-like conformation induces neutralising antibodies in mice, highlighting the importance of antigenic conformation for vaccine design.

This study investigates the phenotypic effects of naturally occurring MERS-CoV Spike mutations on virus entry and neutralisation, identifying mutations that enhance entry or confer resistance to neutralisation.

This study identifies cross-neutralizing mAbs against diverse bat sarbecoviruses and characterizes their conserved epitopes for vaccine design.

This study examines the host range and antigenicity of bat sarbecoviruses, finding that generalist ACE2 users are more related to SARS-CoV-2 and show broader cross-neutralization.

This study identifies the pseudoknot region and poly-(C) tract as essential RNA packaging signals for foot-and-mouth disease virus (FMDV) assembly, showing that their length and interactions influence packaging efficiency.

The paper analyzes antibody neutralization data from multiple countries to assess how prior exposure to SARS-CoV-2 variants affects neutralization profiles of BA.2.86 and its descendants.