Low frequency somatic copy number alterations in normal human lymphocytes revealed by large scale single-cell whole genome profiling
Lu Liu, He Chen, Cheng Sun, Jianyun Zhang, Juncheng Wang, Meijie Du, Lin Di, Jie Shen, Shuang Geng, Yuhong Pang, Yingying Luo, Yusi Fu, Zhe Zheng, Jianbin Wang, Yanyi Huang
The paper uses single-cell whole genome sequencing to identify low frequency somatic copy number alterations in normal human lymphocytes, finding 7.5% of cells have large-size copy number alterations.
Genome Research · Jan 1, 2022Peer-reviewedGenomics