Yuhong Pang

This paper introduces PRISM, a method for high-plex spatial RNA imaging using color intensity barcodes, validated across multiple tissues and showing the role of CAFs in tumor microenvironments.

A fuzzy sequencer improves information efficiency and accuracy in DNA resequencing applications.

The paper introduces SPRINTseq, a spatial transcriptomics method that enables fast, sensitive, and high-resolution data acquisition, revealing cellular and subcellular molecular architecture in Alzheimer's disease.

SHERRY2 is a single-cell RNA sequencing protocol that improves sensitivity and accuracy by eliminating second-strand cDNA synthesis, outperforming existing methods in detecting low-abundance transcripts and specific gene functions.

The paper uses single-cell whole genome sequencing to identify low frequency somatic copy number alterations in normal human lymphocytes, finding 7.5% of cells have large-size copy number alterations.