Author
Peking University
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
6 papers
Recent·Most cited
Wenxiong Zhou, Kang Li, Shuo Qiao, Haifeng Duan, Chenghong Yin, Chao Liu, Zhizhao Liao, Mingchuan Tang, Ruiying Zhang, Lei Li, Lei Shi, Meijie Du, Yipeng Wang, Wentao Yue, Yan Xiao, , Yanyi Huang
A fuzzy sequencer improves information efficiency and accuracy in DNA resequencing applications.
Nature Biomedical Engineering · Jul 2, 2025Peer-reviewedGenomics
Lin Di, Bo Liu, Yuzhu Lyu, Shihui Zhao, Yuhong Pang, Chen Zhang, Jianbin Wang, Hai Qi, Jie Shen, Yanyi Huang
SHERRY2 is a single-cell RNA sequencing protocol that improves sensitivity and accuracy by eliminating second-strand cDNA synthesis, outperforming existing methods in detecting low-abundance transcripts and specific gene functions.
BMC Biology · Sep 29, 2022Peer-reviewedGenomics
Lu Liu, He Chen, Cheng Sun, Jianyun Zhang, Juncheng Wang, Meijie Du, Lin Di, Jie Shen, Shuang Geng, Yuhong Pang, Yingying Luo, Yusi Fu, Zhe Zheng, Jianbin Wang, Yanyi Huang
The paper uses single-cell whole genome sequencing to identify low frequency somatic copy number alterations in normal human lymphocytes, finding 7.5% of cells have large-size copy number alterations.
Genome Research · Jan 1, 2022Peer-reviewedGenomics
Ruoyan Li, Lin Di, Jie Li, Wenyi Fan, Yachen Liu, Wenjia Guo, Weiling Liu, Lu Liu, Qiong Li, Liping Chen, Yamei Chen, Chuanwang Miao, Hongjin Liu, Yuqian Wang, Yuling Ma, , Chen Hsuan Wu
The paper maps somatic mutations and clonal expansions in normal human tissues across nine organs, revealing organ-specific patterns of mutation accumulation and clonal evolution.
Nature · Aug 25, 2021Peer-reviewedGenomics
Chen Chen, Jizhou Li, Lin Di, Qiuyu Jing, Pengcheng Du, Chuan Song, Jiarui Li, Qiong Li, Yunlong Cao, Xiaoliang Sunney Xie, Angela Ruohao Wu, Hui Zeng, Yanyi Huang, Jianbin Wang
MINERVA enables rapid, high-quality SARS-CoV-2 whole genome sequencing from clinical samples by simplifying library preparation and improving viral enrichment.
Molecular Cell · Nov 20, 2020Peer-reviewedMolecular Biology
Lin Di, Yusi Fu, Yue Sun, Jie Li, Lu Liu, Jiacheng Yao, Guanbo Wang, Yalei Wu, Kaiqin Lao, Raymond W. Lee, Genhua Zheng, Jun Xu, Juntaek Oh, Dong Wang, X. Sunney Xie, , Jianbin Wang
This paper introduces SHERRY, a new RNA-seq method that avoids second strand synthesis by using Tn5 transposase to directly fragment and prime RNA/DNA hybrids, improving reproducibility and GC uniformity.
Proceedings of the National Academy of Sciences · Jan 27, 2020Peer-reviewedMolecular Biology