Author

Yohsuke Ohba

Keio University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Elena I. RugarliiD· 2 shared Hendrik NolteiD· 2 shared Maria PatróniD· 2 shared Thomas LangeriD· 2 shared Yvonne Lasarzewski· 2 shared Akinori EiyamaiD· 1 shared Alfredo Cabrera‐OreficeiD· 1 shared Daryna Tarasenko· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCell Biology

Elena I. RugarliORCID

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2 papers

Recent·Most cited

AFG3L2-mediated proteolysis restricts mitochondrial biogenesis and gene expression in hypoxia

Srikanth Chandragiri, Nils Grotehans, Yvonne Lasarzewski, Maria Patrón, Thomas MacVicar, Yohsuke Ohba, Steffen Hermans, Elena I. Rugarli, Hendrik Nolte, Thomas Langer

This study identifies AFG3L2-mediated proteolysis as a mechanism that restricts mitochondrial biogenesis and gene expression under hypoxia by degrading key mitochondrial proteins.

bioRxiv · Sep 27, 2024 · PreprintCell Biology

Regulation of mitochondrial proteostasis by the proton gradient

Maria Patrón, Daryna Tarasenko, Hendrik Nolte, Lara Kroczek, Mausumi Ghosh, Yohsuke Ohba, Yvonne Lasarzewski, Zeinab Alsadat Ahmadi, Alfredo Cabrera‐Orefice, Akinori Eiyama, Tim Kellermann, Elena I. Rugarli, Ulrich Brandt, Michael Meinecke, Thomas Langer

The paper shows that the mitochondrial proton gradient regulates the m-AAA protease AFG3L2 through TMBIM5, linking protein turnover to mitochondrial energy status and Ca2+ signaling.

The EMBO Journal · Aug 1, 2022Peer-reviewedMolecular Biology