The ERAD ubiquitin ligase Doa10 negatively regulates Atg32-mediated mitophagy
Akinori Eiyama, Mashun Onishi, Hana Štupica, Yukiko Omi, Sachiyo Nagumo, Kunio Nakatsukasa, Koji Okamoto
The paper shows that Doa10, an ERAD ubiquitin ligase, interacts with Atg32 to regulate its degradation, thereby negatively controlling mitophagy in yeast.
bioRxiv · Apr 8, 2024 · PreprintCell Biology