Author

Yongjie Yang

Tufts University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Neuroscience· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Organism:human· 1

Frequent Co-Authors

Martin PaukertiD· 2 shared Xuan CheniD· 2 shared Alexandre ChamprouxiD· 1 shared Angelica Salinas· 1 shared Ashley Kim· 1 shared Eunice Y. Lim· 1 shared Haichao WeiiD· 1 shared Huilan Yan· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersNeuroscience

Martin PaukertORCID

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3 papers

Recent·Most cited

Genetic suppression of myeloid receptor Clec7a attenuates microglia neuroinflammation and promotes microglial phagocytosis to delay disease progression in ALS models

Xuan Chen, Huilan Yan, Haichao Wei, Sanaz Sajadi, Jingwen Hu, Vinicius Matos Vasconcellos, Ashley Kim, Tarun Shriram, Huizhong Tan, Kyoeun Keum, Jiaqian Wu, Martin Paukert, Yongjie Yang

This study shows that reducing Clec7a in microglia reduces neuroinflammation and improves phagocytosis, slowing ALS progression in mouse models.

bioRxiv · May 7, 2026 · PreprintNeuroscience

Astrocyte-Derived Exosomes Regulate Sperm miR-34c Levels to Mediate the Transgenerational Effects of Paternal Chronic Social Instability Stress

Alexandre Champroux, Mitra‐Sadat Sadat‐Shirazi, Xuan Chen, Jonathan Hacker, Yongjie Yang, Larry A. Feig

This study shows that paternal chronic social instability stress reduces sperm miR-34c levels via astrocyte-derived exosomes, which are transmitted to offspring and contribute to transgenerational stress-related traits.

Epigenetics · Jan 27, 2025Peer-reviewedGenetics

Impaired neuromodulator crosstalk delays vigilance-dependent astroglia Ca2+ activation in mouse models of Alzheimer's disease

Eunice Y. Lim, Angelica Salinas, Liang Ye, Yongjie Yang, Martin Paukert

The paper shows that impaired neuromodulator crosstalk in AD mouse models leads to delayed and less coordinated astrocyte Ca2+ activation during locomotion.

bioRxiv · Jun 27, 2022 · PreprintNeuroscience