Author

Yongjun Chu

The University of Texas Southwestern Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Molecular Biology· 4

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 4 Research Focus:differential expression· 4 Organism:human· 4 Approach:experimental assay· 3 Research Focus:benchmarking· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

David R. CoreyiD· 4 shared Jing LiuiD· 3 shared Audrius Kilikevičius· 2 shared Krystal C. JohnsoniD· 2 shared Shinnichi Yokota· 2 shared C. Bradley Bowman· 1 shared Chao XingiD· 1 shared Hanquan Liang· 1 shared

Activity by Year

2020-2021 · peak 2/yr

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10 top collaborators · 25 mutual co-author links

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4 shared papersMolecular Biology

David R. CoreyORCID

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4 papers

Recent·Most cited

Impact of scaffolding protein TNRC6 paralogs on gene expression and splicing

Samantha T. Johnson, Yongjun Chu, Jing Liu, David R. Corey

The paper investigates the functional roles of TNRC6 paralogs in RNA-mediated gene expression and splicing using knockout cell lines and RNAseq, finding they are largely redundant with AGO.

RNA · Jun 9, 2021Peer-reviewedMolecular Biology

Argonaute Binding within Human Nuclear RNA and its Impact on Alternative Splicing

Yongjun Chu, Shinnichi Yokota, Jing Liu, Audrius Kilikevičius, Krystal C. Johnson, David R. Corey

This study maps AGO2 binding sites in nuclear RNA and shows miRNAs and intronic regions influence alternative splicing through synthetic RNA experiments.

RNA · Jun 9, 2021Peer-reviewedMolecular Biology

Argonaute Binding within 3'-Untranslated Regions Does Not Predict Gene Repression

Yongjun Chu, Audrius Kilikevičius, Jing Liu, Krystal C. Johnson, Shinnichi Yokota, David R. Corey

The paper investigates the relationship between AGO binding in 3'-UTRs and gene repression, finding that AGO binding does not consistently correlate with gene repression.

Nucleic Acids Research · May 26, 2020Peer-reviewedMolecular Biology

Analyzing Presymptomatic Tissue to Gain Insights into the Molecular and Mechanistic Origins of Late-Onset Degenerative Trinucleotide Repeat Disease

Yongjun Chu, Jiaxin Hu, Hanquan Liang, Mohammed Kanchwala, Chao Xing, Walter E. Beebe, C. Bradley Bowman, Xin Gong, David R. Corey, V. Vinod Mootha

The paper uses RNAseq to compare presymptomatic and late-stage FECD tissue, finding early splicing and gene expression changes that predict fibrosis and immune activation in late-stage disease.

Nucleic Acids Research · May 11, 2020Peer-reviewedMolecular Biology