Mohammed Kanchwala

GMIP-PLSR improves GWAS gene prioritization by integrating multi-omics data using PLSR to address multicollinearity, outperforming PoPS in NAFLD case studies.

This study shows TP53 promotes neural lineage commitment in hESCs by regulating ciliogenesis and Shh signaling through BBS9.

This study shows that STAG2-cohesin promotes myelination by generating promoter-anchored loops at myelination genes in oligodendrocytes, linking cohesin dysfunction to myelination defects in cohesinopathy.

The paper uses RNAseq to compare presymptomatic and late-stage FECD tissue, finding early splicing and gene expression changes that predict fibrosis and immune activation in late-stage disease.