Author

You Che

National Institutes of Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:metagenomics· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Adrien D. Le GuenneciD· 1 shared Ahelee Rahman· 1 shared Aina Navaz Punet· 1 shared Alice YoungiD· 1 shared Andrew Knox· 1 shared Angela Young· 1 shared Anna Bourke· 1 shared Anne‐Louise PonsonbyiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMicrobiology

Adrien D. Le GuennecORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Isoleucine and asparagine influence the growth of staphylococcal strains in atopic dermatitis

Hogan Kok-Fung Wai, Xiaoye Wang, Clement Ching Yin Li, Gilbert T. Chua, Christina Sze Man Wong, Jaime S. Rosa Duque, Vivian Wai Yan Chan, Adrien D. Le Guennec, Jie Zhu, Shabnan Khan, Aina Navaz Punet, Mengzhen Ji, Jingmian Zhang, Elle Simone Hill, You Che, , David L. Moyes

The paper investigates how isoleucine and asparagine affect the growth of staphylococcal strains in atopic dermatitis, finding they promote S. aureus growth and inhibit S. hominis growth.

bioRxiv · Sep 16, 2026 · PreprintMicrobiology

Deciphering the microbial landscape of lower respiratory tract in health and respiratory diseases

Cheng Cheng, Yangqian Li, Suyan Wang, Haoyu Wang, Dan Liu, Qinglan Wang, You Che, Linlin Xue, Ningning Chao, Xuan He, Chengping Li, Huohua Tian, Jing Zhou, Xin Wang, Yurui Yang, , Weimin Li

This study characterizes the lung microbiome in health and respiratory diseases using metagenomic sequencing, identifying key species and functional pathways associated with different conditions.

bioRxiv · Jun 11, 2025 · PreprintMicrobiology

A genome catalog of the early-life human skin microbiome

Zeyang Shen, Lukian Robert, Milan Stolpman, You Che, Katrina Jane Allen, Richard Saffery, Audrey Walsh, Angela Young, Jana Eckert, Clay Deming, Qiong Chen, Sean Conlan, Karen Laky, Jenny Min Li, Lindsay Chatman, , Carrie Service

The paper presents a genome catalog of the early-life human skin microbiome, expanding diversity and improving classification rates using metagenomic data from infants and their mothers.

Genome biology · Nov 9, 2023Peer-reviewedGenomics