NeuroscienceeLifePeer-reviewed
Coupling of Slack and NaV1.6 sensitizes Slack to quinidine blockade and guides anti-seizure strategy development
Yuan Tian, Yifan Wang, Yuchen Jin…·Zhuo Huang
The paper identifies a functional coupling between Slack and NaV1.6 that enhances quinidine blockade of Slack, suggesting a new approach for treating KCNT1-related epilepsy.
8 citations