Ali D. Güler

LiFE, a circadian intervention combining light, food, and exercise, improves sleep, glycemic control, and memory in mice.

The paper shows that the balance of BDNF receptors TrkB and p75NTR in AgRP neurons controls PVH fiber density and stimulation-evoked feeding across different caloric states.

This paper shows small-molecule GLP1RAs modulate reward processing via a specific neural circuit in the central amygdala, affecting dopamine release and hedonic feeding.

The paper identifies a neural circuit involving TrhArc neurons that mediate the appetite-suppressing effects of GLP-1RAs by inhibiting AgRP neurons.

This study shows that mice lacking dopamine production in neurotensin receptor 1 neurons resist obesity on a high fat diet by not increasing daytime eating.

This study identifies that dorsal motor vagal neurons can cause bradycardia and reduce anxiety-like behavior through specific receptor mechanisms.

This study investigates circadian re-entrainment in Alzheimer's disease mouse models, finding faster re-entrainment in 3xTg and 5xFAD mice, independent of microglia or tau pathology, suggesting altered light sensing contributes to circadian behavior changes.

The paper identifies a leptin-responsive hypothalamic circuit that influences circadian feeding rhythms by modulating SCN activity and food entrainment.