CTCF looping is established during gastrulation in medaka embryos
Ryohei Nakamura, Yuichi Motai, Masahiko Kumagai, Candice L. Wike, Haruyo Nishiyama, Yoichiro Nakatani, Neva C. Durand, Kaori Kondo, Takashi Kondo, Tatsuya Tsukahara, Atsuko Shimada, Bradley Robert Cairns, Erez Lieberman Aiden, Shinichi Morishita, Hiroyuki Takeda
The paper examines genome architecture changes during medaka gastrulation, finding that CTCF loops form while CTCF binding sites remain fixed, and transcription precedes mature domain formation.
Genome Research · Jun 1, 2021Peer-reviewedGenomics