Vibrio cholerae RbmB is an α-1,4-polysaccharide lyase with biofilm-dispersal activity against Vibrio Polysaccharide (VPS)
Ranjuna Weerasekera, Alexis Moreau, Xin Huang, Kee-Myoung Nam, Alex Hinbest, Yun Huynh, Xinyu Liu, Christopher Ashwood, Lauren E. Pepi, Eric K. Paulson, Lynette Cegelski, Jing Quan Yan, Rich Olson
This study identifies RbmB as a polysaccharide lyase that cleaves Vibrio cholerae VPS, contributing to biofilm dispersal and suggesting its potential as an antibacterial enzyme.
PLoS Pathogens · Dec 2, 2024Peer-reviewedBiochemistry