Author

Lauren E. Pepi

Beth Israel Deaconess Medical CenterORCID 0000-0002-5740-4175Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:proteomics· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Alex Hinbest· 1 shared Alexis MoreauiD· 1 shared Christopher AshwoodiD· 1 shared Eric K. PaulsoniD· 1 shared Jing Quan YaniD· 1 shared Kee-Myoung NamiD· 1 shared Lynette CegelskiiD· 1 shared Nicholas McIlvain RileyiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBiochemistry

Alex Hinbest

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2 papers

Recent·Most cited

Comparative Analysis of Glycoproteomic Software Using a Tailored Glycan Database

Reuben A. Hogan, Lauren E. Pepi, Nicholas McIlvain Riley, Robert J. Chalkley

This paper compares five glycoproteomic software tools using a tailored glycan database, finding that Protein Prospector has the highest agreement with known glycosites.

Analytical and Bioanalytical Chemistry · Mar 17, 2025Peer-reviewedBioinformatics

Vibrio cholerae RbmB is an α-1,4-polysaccharide lyase with biofilm-dispersal activity against Vibrio Polysaccharide (VPS)

Ranjuna Weerasekera, Alexis Moreau, Xin Huang, Kee-Myoung Nam, Alex Hinbest, Yun Huynh, Xinyu Liu, Christopher Ashwood, Lauren E. Pepi, Eric K. Paulson, Lynette Cegelski, Jing Quan Yan, Rich Olson

This study identifies RbmB as a polysaccharide lyase that cleaves Vibrio cholerae VPS, contributing to biofilm dispersal and suggesting its potential as an antibacterial enzyme.

PLoS Pathogens · Dec 2, 2024Peer-reviewedBiochemistry