Author

H.-J. Paust

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

C. F. Krebs· 4 shared T. B. Huber· 4 shared N. Song· 3 shared Y. Zhao· 3 shared A. Borchers· 2 shared A. Kaffke· 2 shared A. Peters· 2 shared A. Sivayoganathan· 2 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersImmunology

C. F. Krebs

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4 papers

Recent·Most cited

The integrated stress response/eIF2α pathway controls cytokine production in tissue-resident memory CD4+ T cells

N. Asada, P. Ginsberg, H.-J. Paust, N. Song, J.-H. Riedel, J.-E. Turner, A. Peters, A. Kaffke, J. Engesser, H. Wang, Y. Zhao, P. Gild, R. Dahlem, S. Das, Z. Ignatova, , U. Panzer

This study shows that the ISR/eIF2α pathway regulates cytokine mRNA translation in Trm cells, limiting their activity in homeostasis but enabling rapid response during inflammation or autoimmunity.

bioRxiv · Jan 26, 2024Immunology

Emergence and suppressive function of Tr1 cells in glomerulonephritis

S. Soukou-Wargalla, C. Kilian, L. Velasquez, A. Machicote, F. Stumme, T. Bedke, A. Giannou, J. Kempski, M. Sabihi, N. Song, H.-J. Paust, A. Borchers, L. G. Perez, P. Pelczar, B. Liu, , S. Huber

This study identifies Tr1 cells in glomerulonephritis, showing their suppressive function and potential as therapeutic targets.

bioRxiv · Feb 7, 2023Immunology

Transcriptional and clonal characterization of cytotoxic CD8+ T cells in crescentic glomerulonephritis

Y. Zhao, A. Mueller, H. Cicek, H.-J. Paust, A. Sivayoganathan, A. Linke, C. Wegscheid, T. Wiech, T. B. Huber, C. Meyer-Schwesinger, S. Bonn, U. P. Panzer, G. Tiegs, C. F. Krebs, K. Neumann

This study identifies clonally expanded cytotoxic CD8+ T cells in ANCA-associated cGN and shows their pathogenic role in kidney disease progression.

bioRxiv · Aug 31, 2022Immunology

GM-CSF drives immune-mediated glomerular disease by licensing monocyte-derived cells to produce MMP12

H.-J. Paust, N. Song, D. DeFeo, N. Asada, S. Tuzlak, Y. Zhao, J.-H. Riedel, M. Hellmig, A. Sivayoganathan, A. Peters, A. Kaffke, A. Borchers, U. O. Wenzel, O. M. S. M. Steinmetz, G. Tiegs, , U. P. Panzer

The paper identifies GM-CSF-producing T cells that drive glomerulonephritis by licensing monocyte-derived cells to produce MMP12, leading to renal tissue damage.

bioRxiv · Jun 13, 2022Immunology