Author

Z. Lao

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Bioengineering· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Organism:human· 3 Research Focus:clustering· 2 Approach:deep learning· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

Z. Jiang· 2 shared B. Zhang· 1 shared D. Zhuang· 1 shared E. Gazit· 1 shared G. Li· 1 shared G. Wei· 1 shared H. Wang· 1 shared J. Wu· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersBioengineering

Z. Jiang

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Beyond enumeration: Phenotype independent "labeling-capture-release" process enabling precise detection of circulating tumour cells and downstream applications

Z. Lao, X. Ren, D. Zhuang, L. Xie, Y. Zhang, W. Li, Z. Jiang, Y. Chen, P. Li, L. Tong, P. K. Chu, H. Wang

This paper introduces a labeling-capture-release method for isolating circulating tumor cells from blood samples with high efficiency and accuracy, enabling downstream applications.

bioRxiv · Mar 27, 2024 · PreprintBioengineering

OpenNucleome for high resolution nuclear structural and dynamical modeling

Z. Lao, K. D. Kamat, Z. Jiang, B. Zhang

OpenNucleome enables GPU-accelerated molecular dynamics simulations of the human nucleus to model structural organization and dynamic processes, revealing mechanisms of genomic anchoring and nuclear zoning.

bioRxiv · Oct 16, 2023Biophysics

DENV NS1 and MMP-9 cooperate to induce vascular leakage by altering endothelial cell adhesion and tight junction

G. Li, P. Pan, M. Shen, Z. Yu, W. Ge, Z. Lao, Y. Fan, K. Chen, Z. Ding, W. Wang, P. Wan, M. A. Shereen, Z. Luo, X. Chen, Q. Zhang, , J. Wu

This study identifies that DENV NS1 and MMP-9 cooperate to induce vascular leakage by altering endothelial cell adhesion and tight junctions, suggesting MMP-9 as a potential therapeutic target for severe dengue.

PLOS Pathogens · Jul 26, 2021Peer-reviewedMicrobiology

Dipeptides are minimalistic but sufficient for liquid-liquid phase separation

Y. Tang, S. Bera, Y. Yao, J. Zeng, Z. Lao, X. Dong, E. Gazit, G. Wei

This study identifies dipeptides as minimalistic yet sufficient for liquid-liquid phase separation through computational and experimental methods.

bioRxiv · Apr 3, 2021Biophysics