Author

P. Galanos

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:whole-genome sequencing· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Assay:DNA methylation· 2 Approach:experimental assay· 2 Approach:statistical model· 2

Frequent Co-Authors

J. Bartek· 3 shared A. Polyzos· 2 shared A. Angelopoulou· 1 shared A. Georgakilas· 1 shared A. Kotsinas· 1 shared A. Maya-Mendoza· 1 shared A. Papantonis· 1 shared A. R. Chaudhuri· 1 shared

Activity by Year

2017-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersCancer Biology

J. Bartek

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Author profile →

3 papers

Recent·Most cited

Loss of Nuclear DNA Ligase III Reverts PARP Inhibitor Resistance in BRCA1/53BP1 Double-deficient Cells by Exposing ssDNA Gaps

M. Paes Dias, V. Tripathi, I. v. d. Heijden, K. Cong, E.-M. Manolika, J. Bhin, E. Gogola, P. Galanos, S. Annunziato, C. Lieftink, M. Andujar-Sanchez, S. Chakrabarty, G. C. M. Smith, M. v. d. Ven, R. L. Beijersbergen, , J. Jonkers

This study identifies loss of LIG3 as a factor that reverts PARP inhibitor resistance in BRCA1/53BP1 double-deficient cells by increasing ssDNA gaps.

bioRxiv · Mar 24, 2021 · PreprintCancer Biology

Genomic instability is an early event driving chromatin reorganization and escape from oncogene-induced senescence

C. Zampetidis, P. Galanos, A. Angelopoulou, Y. Zhu, T. Karamitros, N. Lagopati, R. Mirzazadeh, A. Polyzos, S. Garnerone, E. G. Gusmao, K. Sofiadis, D. E. Pefani, M. Demaria, N. Crosetto, A. Maya-Mendoza, , V. G. Gorgoulis

The paper identifies an early chromosomal inversion that enables escape from oncogene-induced senescence by activating BHLHE40 and promoting malignant transformation.

bioRxiv · Dec 20, 2020Cell Biology

Mutational signatures reveal the role of RAD52 in p53-independent p21 driven genomic instability

P. Galanos, G. Pappas, A. Polyzos, A. Kotsinas, I. Svolaki, N. Giakoumakis, C. Glytsou, I. Pateras, U. Swain, V. Souliotis, A. Georgakilas, N. Geacintov, L. Scorrano, C. Lukas, J. Lukas, , V. Gorgoulis

This study shows chronic p21WAF1/Cip1 expression causes genomic instability by suppressing DNA repair pathways, revealing Rad52 as a key player in this process.

bioRxiv · Sep 28, 2017Cancer Biology