Author

Z. W. Zeng

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Organism:rat· 1

Frequent Co-Authors

C. Bear· 1 shared C. E. Ing· 1 shared E. A. Fon· 1 shared H. Cui· 1 shared J. Ereno-Oreba· 1 shared J.-F. Trempe· 1 shared J.-P. Julien· 1 shared M. A. Eldeeb· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

C. Bear

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Structure-based design and characterization of Parkin activating mutations

J.-F. Trempe, M. U. Stevens, N. Croteau, M. A. Eldeeb, Z. W. Zeng, R. Toth, T. M. Durcan, W. Springer, E. A. Fon, M. M. K. Muqit

The paper identifies three Parkin activating mutations that rescue mitophagy defects in cell-based studies, suggesting therapeutic potential for Parkinson's disease.

bioRxiv · Feb 22, 2022Biochemistry

Lipid interactions enhance activation and potentiation of cystic fibrosis transmembrane conductance regulator (CFTR)

S. Chin, M. Ramjeesingh, M. Hung, J. Ereno-Oreba, C. E. Ing, Z. W. Zeng, H. Cui, J.-P. Julien, R. Pomes, C. Bear

This study shows that lipid interactions are crucial for CFTR channel activation and potentiation, as demonstrated by higher catalytic activity and response to ivacaftor when CFTR is purified with associated lipids.

bioRxiv · Dec 16, 2018 · PreprintBiophysics