Author

Zackary A. Cope

Medical University of South Carolina

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Adrian L. OblakiD· 1 shared Ankit Nagar· 1 shared Arthur C. RiegeliD· 1 shared Brandon S. BentzleyiD· 1 shared Brittney M. CoxiD· 1 shared Bruce T. LambiD· 1 shared Christina M. RuiziD· 1 shared Duc M. Duong· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperNeuroscience

Adrian L. OblakORCID

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2 papers

Recent·Most cited

Molecular mechanisms underlying amyloid lowering by aducanumab: differential and comparative effects of sex and IgG reveal the post-treatment disease brain

Kathryn A. Haynes, Ravi S. Pandey, Emma H. Doud, Zackary A. Cope, Gabriela J. Little, Sean-Paul Williams, Umesh Nepali, Sara K. Quinney, Ankit Nagar, Nitin Charbe, Lais Da Silva, Jeffrey L. Dage, Duc M. Duong, Nicholas T. Seyfried, Michael Sasner, , Stacey J. Sukoff Rizzo

This study examines the molecular effects of aducanumab treatment in 5XFAD mice, revealing sex-dependent and IgG-mediated changes in amyloid and associated pathways.

bioRxiv · Jun 21, 2026 · PreprintNeuroscience

Chemogenetic Manipulations of Ventral Tegmental Area Dopamine Neurons Reveal Multifaceted Roles in Cocaine Abuse

Stephen V. Mahler, Zachary D. Brodnik, Brittney M. Cox, William C. Buchta, Brandon S. Bentzley, Julian Quintanilla, Zackary A. Cope, Edwin C Lin, Matthew D. Riedy, Michael D. Scofield, Justin Messinger, Christina M. Ruiz, Arthur C. Riegel, Rodrigo A. España, Gary Aston‐Jones

The paper uses chemogenetic manipulation to explore the role of VTA dopamine neuron G-protein signaling in cocaine-related behaviors, revealing distinct effects based on signaling pathways and behavioral context.

Journal of Neuroscience · Nov 16, 2018Peer-reviewedNeuroscience