Author

William C. Buchta

Medical University of South CarolinaORCID 0000-0002-7489-9624Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Organism:rat· 1

Frequent Co-Authors

Arthur C. RiegeliD· 3 shared Aubin MoutaliD· 2 shared Peter W. KalivasiD· 2 shared Rajesh KhannaiD· 2 shared Abigail Lauer· 1 shared Alexander C.W. SmithiD· 1 shared Benjamin A. HarlaniD· 1 shared Bethany Hines· 1 shared

Activity by Year

2018-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersNeuroscience

Arthur C. RiegelORCID

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3 papers

Recent·Most cited

Dynamic CRMP2 regulation of CaV2.2 in the prefrontal cortex contributes to the reinstatementof cocaine seeking

William C. Buchta, Aubin Moutal, Bethany Hines, Constanza García‐Keller, Alexander C.W. Smith, Peter W. Kalivas, Rajesh Khanna, Arthur C. Riegel

This study investigates how CRMP2 and CaV2.2 interactions in the prefrontal cortex influence cocaine-seeking behavior and relapse.

Molecular Neurobiology · Jul 29, 2019Peer-reviewedNeuroscience

Chemogenetic Manipulations of Ventral Tegmental Area Dopamine Neurons Reveal Multifaceted Roles in Cocaine Abuse

Stephen V. Mahler, Zachary D. Brodnik, Brittney M. Cox, William C. Buchta, Brandon S. Bentzley, Julian Quintanilla, Zackary A. Cope, Edwin C Lin, Matthew D. Riedy, Michael D. Scofield, Justin Messinger, Christina M. Ruiz, Arthur C. Riegel, Rodrigo A. España, Gary Aston‐Jones

The paper uses chemogenetic manipulation to explore the role of VTA dopamine neuron G-protein signaling in cocaine-related behaviors, revealing distinct effects based on signaling pathways and behavioral context.

Journal of Neuroscience · Nov 16, 2018Peer-reviewedNeuroscience

Restoration of Kv7 channel mediated inhibition reduces cued-reinstatement of cocaine seeking

Jeffrey Parrilla-Carrero, William C. Buchta, Priyodarshan Goswamee, Oliver Paul Culver, Greer McKendrick, Benjamin A. Harlan, Aubin Moutal, Rachel D. Penrod, Abigail Lauer, Viswanathan Ramakrishnan, Rajesh Khanna, Peter W. Kalivas, Arthur C. Riegel

This study identifies a subpopulation of prelimbic cortex neurons that become hyperexcitable after chronic cocaine exposure, and shows that restoring Kv7 channel function reduces cue-induced cocaine seeking.

Journal of Neuroscience · Apr 10, 2018Peer-reviewedNeuroscience