Periaqueductal gray neurotensin neurons drive simultaneousthreat response and reinforcement
Grace O Davis, Siyi Ma, McKenna Kernan, Dustin Sumarli, Mary C. Loveless, Kyle W Schroeder, Su G. Cho, Zainab Nasir, Micaela V. Ruiz, Marta E. Soden
The paper identifies PAG-Nts neurons that co-release glutamate and neurotensin to activate dopamine neurons, driving both threat responses and operant reinforcement behaviors.
bioRxiv · Feb 17, 2026 · PreprintNeuroscience