Endothelial cell Piezo1 promotes vascular smooth muscle cell differentiation on large arteries
Javier Abello, Ying Yin, Yonghui Zhao, Josh Maurer, Jihui Lee, Cherokee Bodell, Jahmiera Richee, Abigail J. Clevenger, Zarek Burton, Megan E. Goeckel, Michelle J. Lin, Stephanie J. Grainger, Carmen M. Halabi, Shreya A. Raghavan, Rajan Sah, Amber N. Stratman
This study shows that endothelial Piezo1 regulates vascular smooth muscle cell differentiation in zebrafish and mice by modulating klf2a levels and flow force sensing.
European Journal of Cell Biology · Dec 20, 2024Peer-reviewedDevelopmental Biology