This study shows that endothelial Piezo1 regulates vascular smooth muscle cell differentiation in zebrafish and mice by modulating klf2a levels and flow force sensing.

European Journal of Cell Biology · Dec 20, 2024Peer-reviewedDevelopmental Biology

Genome sequencing of 196 Treponema pallidum strains from six continents reveals additional variability in vaccine candidate genes and dominance of Nichols clade strains in Madagascar

Nicole A. P. Lieberman, Michelle J. Lin, Hong Jian Xie, Lasata Shrestha, Tien V. Nguyen, Meei-Li W. Huang, Austin M. Haynes, Emily Romeis, Qianqiu Wang, Ruili Zhang, Cai-Xia Kou, Giulia Ciccarese, Ivano Dal Conte, Marco Cusini, Francesco Drago, , Alexander L. Greninger

PLoS neglected tropical diseases · Dec 22, 2021Peer-reviewedGenomics

LAVA: a streamlined visualization tool for longitudinal analysis of viral alleles

Michelle J. Lin, Ryan C. Shean, Negar Makhsous, Alexander L. Greninger

LAVA is a command-line tool for visualizing longitudinal viral genome evolution, generating interactive HTML results for analysis and sharing.

bioRxiv · Dec 17, 2019 · PreprintBioinformatics

VAPiD: a lightweight cross platform viral annotation pipeline and identification tool to facilitate virus genome submissions to NCBI GenBank

Ryan C. Shean, Negar Makhsous, Graham D. Stoddard, Michelle J. Lin, Alexander L. Greninger

VAPiD annotates and submits viral genomes to NCBI GenBank, supporting multiple virus types and operating across platforms.

BMC Bioinformatics · Jan 23, 2019Peer-reviewedBioinformatics