Carmen M. Halabi

The paper compares the developmental strategies of the enteric nervous system and intrinsic cardiac nervous system to reveal how organ-specific specialization occurs through distinct molecular and cellular mechanisms.

This study identifies LRRC8C as a non-redundant component of the endothelial LRRC8 complex that regulates vascular reactivity and blood pressure.

The paper shows synaptopodin enables cells to adapt their adhesion structures to resist perpendicular forces by reorganizing the actin cytoskeleton and integrin-based adhesions.

The paper identifies a mechanical homeostasis mechanism in podocytes where balance between fluid shear stress and cellular contractility prevents injury, showing that reducing blood pressure can worsen outcomes when contractility is impaired.

This study shows that endothelial Piezo1 regulates vascular smooth muscle cell differentiation in zebrafish and mice by modulating klf2a levels and flow force sensing.