Author

Zhihui Qi

Harvard University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Organism:E. coli· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Abhinav DubeyiD· 1 shared Doeke R. HekstraiD· 1 shared Dongtao CuiiD· 1 shared Eugene I. ShakhnovichiD· 1 shared Fatima Aly· 1 shared Harrison K. WangiD· 1 shared Jiaoyan ReniD· 1 shared João V. RodriguesiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBiophysics

Abhinav DubeyORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Midazolam suppresses glioma progression by attenuating neuronal activity and downregulating IGF1 signaling

Zhihui Qi, Zhiming Ye, Kahei Chan, Yumin Wu, Yu Yu, Yang Hu, Yi Lu, Jiaoyan Ren, Maojin Yao, Zhongxing Wang

This study shows midazolam inhibits glioma growth by reducing neuronal activity and IGF1 signaling in vitro and in vivo.

Acta Biochimica et Biophysica Sinica · Jun 8, 2026Peer-reviewedNeuroscience

Chaperonin recognition of protein dynamics drives drug resistance

Junlang Liu, Zhihui Qi, João V. Rodrigues, Z X Zhang, Qianxiang Xu, Abhinav Dubey, Harrison K. Wang, Dongtao Cui, Zeyang Li, Fatima Aly, Doeke R. Hekstra, Eugene I. Shakhnovich

The paper shows that chaperonin GroEL/S promotes drug resistance by recognizing protein dynamics, displacing inhibitors and restoring active enzyme function.

bioRxiv · Jun 7, 2026 · PreprintBiophysics