Author

Zhiyi Wu

Hammersmith Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Organism:mouse· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Aida Martínez-SáncheziD· 2 shared Guy A. RutteriD· 2 shared Alejandra TomásiD· 1 shared Alina MihalovitsiD· 1 shared Anna Sałówka· 1 shared Annabel Macklin· 1 shared Anusha Thapa· 1 shared Bell Baker· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCell Biology

Aida Martínez-SánchezORCID

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2 papers

Recent·Most cited

MTFP1 preserves β-cell cristae structure and bioenergetics to ensure insulin release and glucose homeostasis

Sunehera Sarwat, Rosa Alén, Zhiyi Wu, Chuyue Zhang, Michal Paszek, MingMing Yang, Giada Ostinelli, Alina Mihalovits, Bell Baker, Timothy Wai, Guy A. Rutter, Tristan A. Rodríguez, Aida Martínez-Sánchez

This study identifies MTFP1 as critical for β-cell mitochondrial structure and function, essential for insulin secretion and glucose homeostasis, and shows its role as a downstream effector of miR-125b.

bioRxiv · Feb 3, 2026 · PreprintCell Biology

Glucose-dependent miR-125b is a negative regulator of β-cell function

Rebecca Cheung, Grazia Pizza, PAULINE L. CHABOSSEAU, Delphine Rolando, Alejandra Tomás, Thomas Burgoyne, Zhiyi Wu, Anna Sałówka, Anusha Thapa, Annabel Macklin, Yufei Cao, Marie‐Sophie Nguyen‐Tu, Matthew T. Dickerson, David Aaron Jacobson, Piero Marchetti, , Aida Martínez-Sánchez

This study identifies miR-125b-5p as a glucose-regulated miRNA that negatively regulates β-cell function by modulating organelle dynamics and insulin secretion.

Diabetes · Apr 27, 2022Peer-reviewedMolecular Biology