Timothy Wai

This study shows maternal obesity accelerates cardiomyocyte maturation in offspring, leading to adult heart dysfunction through cytoarchitectural disruption.

This study shows SARS-CoV-2 ORF9b uses TOMM70 to avoid proteasomal degradation, reduces inflammation, and is not essential for viral replication or lung pathology.

This study shows that loss of CHCHD2 and CHCHD10 causes tissue-specific bioenergetic defects in cardiac and skeletal muscle, leading to distinct pathological outcomes.

This study identifies MTFP1 as critical for β-cell mitochondrial structure and function, essential for insulin secretion and glucose homeostasis, and shows its role as a downstream effector of miR-125b.

This study shows that structured alignment of cardiomyocytes improves mitochondrial function and bioenergetic efficiency, highlighting the role of cellular organization in heart health.

This study shows that mutant CHCHD10 causes mitochondrial dysfunction and cardiomyopathy by disrupting cytochrome c oxidation and activating retrograde signaling.