Author

Delphine Rolando

Imperial College London

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Lorenzo PiemontiiD· 3 shared Anthony BeucheriD· 2 shared Eelco J.P. de KoningiD· 2 shared François N. PattouiD· 2 shared Ignasi MorániD· 2 shared Javier García-HurtadoiD· 2 shared Jorge P. FerreriD· 2 shared Julie A. Kerr-ConteiD· 2 shared

Activity by Year

2016-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenomics

Lorenzo PiemontiORCID

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Author profile →

3 papers

Recent·Most cited

Glucose-dependent miR-125b is a negative regulator of β-cell function

Rebecca Cheung, Grazia Pizza, PAULINE L. CHABOSSEAU, Delphine Rolando, Alejandra Tomás, Thomas Burgoyne, Zhiyi Wu, Anna Sałówka, Anusha Thapa, Annabel Macklin, Yufei Cao, Marie‐Sophie Nguyen‐Tu, Matthew T. Dickerson, David Aaron Jacobson, Piero Marchetti, , Aida Martínez-Sánchez

This study identifies miR-125b-5p as a glucose-regulated miRNA that negatively regulates β-cell function by modulating organelle dynamics and insulin secretion.

Diabetes · Apr 27, 2022Peer-reviewedMolecular Biology

Human pancreatic islet 3D chromatin architecture provides insights into the genetics of type 2 diabetes

Irene Miguel-Escalada, Sílvia Bonàs‐Guarch, Inês Cebola, Joan Ponsa-Cobas, Julen Mendieta-Esteban, Goutham Atla, Biola M. Javierre, Delphine Rolando, Irene Farabella, Claire C. Morgan, Javier García-Hurtado, Anthony Beucher, Ignasi Morán, Lorenzo Pasquali, Mireia Ramos-Rodríguez, , Jorge P. Ferrer

The paper links diabetes-associated enhancers with their target genes using 3D chromatin architecture in human pancreatic islets, revealing genetic variants that impact insulin secretion heritability.

Nature Genetics · Jun 28, 2019Peer-reviewedGenomics

Human pancreatic β cell lncRNAs control cell-specific regulatory networks

İldem Akerman, Zhidong Tu, Anthony Beucher, Delphine Rolando, Claire Sauty-Colace, Marion Benazra, Nikolina Nakić, Jialiang Yang, Huan Wang, Lorenzo Pasquali, Ignasi Morán, Javier García-Hurtado, Natalia Castro, Roser Gonzalez-Franco, Andrew F. Stewart, , Jorge P. Ferrer

This study identifies β cell-specific lncRNAs that regulate transcriptional networks and show dysregulation in type 2 diabetes.

Cell Metabolism · Dec 29, 2016Peer-reviewedGenomics