Lara M. Cassidy

The paper identifies recent positive selection of MEFV mutations in Armenians linked to the first Yersinia pestis plague pandemic, suggesting resistance to plague as the selective agent.

This paper investigates using imputation to improve archaic ancestry inference in ancient human genomes, showing that imputed genomes can reliably detect and quantify introgression and identify introgressed segments.

This study combines palaeoproteomic and genetic analyses to show that dairy consumption in Armenia dates back to the late fourth millennium BCE, but lactase persistence variants remained rare, suggesting cultural adaptations to fermented dairy.

The paper analyzes ancient genomes from Classic Copan, revealing a genetic continuum with dual ancestral structure between Mesoamerican and South American Farmer ancestry.

Low-ABC improves demographic inference from low-coverage whole-genome data by using genotype likelihoods instead of called genotypes, enabling reliable analysis of population history.

The paper imputes diploid genotypes from low-coverage ancient cattle genomes using a modern reference panel, achieving high accuracy and SNP recovery across different downsample depths.

The paper identifies two distinct mutations in the EXT1 gene from medieval Irish individuals with multiple osteochondromas, confirming a paleopathological diagnosis and highlighting genetic variation in ancient populations.

The paper curates a dataset of 34 high-coverage shotgun human genomes, including ancient and modern samples, along with the genetic pipeline used for processing.

This paper models the impact of climate and terrain on human ancestral genetic lineages, showing that these factors explain lineage divergence and migration patterns.

This paper introduces methods to infer population histories using ancient genomes and genealogies, revealing insights into population dynamics and mutation rates in ancient populations.

This study analyzes ancient genomes from the Viking Age to understand genetic structure and migration patterns, finding significant foreign gene flow and population differentiation.

This paper uses haplotype-based methods to reveal genetic structure in Ireland, showing regional diversity and historical migrations, with implications for genetic association studies.

The paper analyzes ancient genomic data from Portugal to study genetic changes during the Neolithic to Bronze Age transition, finding limited genetic influx and correlations between ancestry and stature.