A Agresti

This study shows how different Mycobacterium tuberculosis lineages interact with macrophage phenotypes to affect phagosomal acidification, highlighting the complexity of host-pathogen interactions in tuberculosis.

This study investigates how NF-κB co-activation enhances p53 accumulation dynamics, impairing DNA repair and revealing a transcriptionally mediated antagonism between p53 and NF-κB.

The paper shows that small transcriptional differences between cell clones lead to distinct NF-κB dynamics despite similar transcriptomic profiles.

The paper characterizes the transcriptional response to TNF-α using single-cell analysis, showing heterogeneous gene expression with prompt and sharp population-level dynamics driven by 'first responders'.