Olga Gewartowska

This study shows TENT5A polyadenylates enamel matrix protein mRNAs, enhancing their stability and translation, which is essential for proper enamel mineralization.

This study shows DIS3L is essential for mouse embryo development but not cell viability, as its absence causes severe embryo degeneration and impaired protein synthesis without affecting cell survival or transcriptome levels.

This study shows DIS3 mutations in multiple myeloma increase AID-dependent IgH translocations by altering chromatin interactions and RNA processing.

This study shows that DIS3 mutations in multiple myeloma arise early but are later counterselected due to toxicity, with loss-of-heterozygosity reversing their effects.

A mutation in the TRAP1 gene causes autism-like behaviors in male mice, suggesting a role for mitochondrial protein homeostasis in male-specific autism.

This study identifies TENT5A as a cytoplasmic poly(A) polymerase essential for collagen production and bone formation, revealing its role in osteogenesis imperfecta type XVIII.