Non-invasive peripheral delivery of CDNF fragment protects neurons in models of Parkinsons and ALS
Li Ying Yu, Tuulikki Viljakainen, Liam Beckett, Jin Han Nam, Anu Hyysalo, Patrick Lüningschrör, Katrina Albert, Tapani K Koppinen, Tanja Hyvärinen, Helena Tossavainen, Maarit Hellman, Mikko Airavaara, Michael Sendtner, Perttu Permi, Päivi Lindholm, , Merja H. Voutilainen
This paper demonstrates that a novel C-CDNF fragment can protect neurons in Parkinson's and ALS models through non-invasive peripheral delivery.
bioRxiv · Feb 9, 2025 · PreprintNeuroscience