Mikko Airavaara

This study creates a rat model of adult dopamine loss by knocking out tyrosine hydroxylase and identifies early transcriptional changes, including reduced neuregulin1, in dopaminergic neurons and surrounding cells.

The paper shows that DDHD2-generated saturated fatty acids are essential for neuronal energy production and synaptic function.

This study shows that overexpressing GDNF in the rat striatum changes a low exploratory behavior to highly explorative, suggesting GDNF's role in personality traits and potential therapeutic applications.

This paper demonstrates that a novel C-CDNF fragment can protect neurons in Parkinson's and ALS models through non-invasive peripheral delivery.

The paper shows that PKB/AKT activation protects dopamine neurons from ER stress and -syn aggregation via Cathepsins B and D, suggesting a potential gene therapy approach for Parkinson's disease.

This study identifies Arg1+ microglia as a distinct subtype in female mice, showing their role in cognitive function through dendritic spine maturation and behavior.

This study shows that activating the GDNF/RET signaling pathway prevents Lewy Body pathology in dopamine neurons by blocking α-synuclein aggregation.