Tatsuya Kaminishi

This study identifies the binding site of the antibiotic GE81112 in the ribosomal mRNA channel using cryoEM, showing it acts allosterically to inhibit translation initiation.

The paper uses time-course RNA-seq to study muscle remodeling in Drosophila, identifying BNIP3-mediated mitophagy as critical for mitochondrial degradation during this process.

This study identifies the Rubicon-WIPI axis as a regulator of exosome biogenesis, showing its role in age-dependent exosome release and microRNA fate in mice.

This study determines the structure of KBP-7072 bound to the 30S ribosomal subunit, showing it inhibits protein synthesis by binding to the primary tetracycline site and interacting uniquely with the subunit.