Author

Pedro Nuno Leão

Universidade do PortoORCID 0000-0001-5064-9164Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:metabolomics· 2 Approach:statistical model· 2 Organism:C. elegans· 1 Research Focus:database / resource· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Adriana RegoiD· 2 shared Marine CuauiD· 2 shared Aleksandra E. KorenskaiaiD· 1 shared Alma Trinidad-Javier· 1 shared Amaranta KahniD· 1 shared Anne LiongiD· 1 shared April L. LukowskiiD· 1 shared Ashleigh J. BurkeiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersMicrobiology

Adriana RegoORCID

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3 papers

Recent·Most cited

MicrobiologymBioPeer-reviewedSep 9, 2026

Activation-independent capture of free fatty acids at the bacterial cell envelope by BrtB

Amaranta Kahn, Cristina Isabel Freitas Sousa, João P. A. Reis…·Pedro Nuno Leão

The paper shows that BrtB in Synechocystis captures free fatty acids at the cell envelope without activation, generating B-FAs and suggesting a new pathway for FFA incorporation.

DOI 10.1128/mbio.01132-26

C. elegansmetabolomics

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BioinformaticsACS OmegaPeer-reviewedAug 11, 2026

Computational pipeline reveals nature's untapped reservoir of halogenating enzymes

Judit Szenei, Ashleigh J. Burke, Anne Liong…·Kai Blin

The paper develops a computational pipeline and database to annotate halogenating enzymes in genomic and metagenomic data, revealing underexplored clusters and improving predictions of microbial halogenated natural products.

DOI 10.1021/acsomega.6c02136

metagenomicsstatistical model

𝕏 PostBluesky

MicrobiologyJournal of Natural ProductsPeer-reviewedJun 25, 2026

AI-Accelerated Structure Elucidation of Boavistamides A-C, Cyclic Depsipeptides from a Marine Filamentous Cyanobacterium Collected in Cabo Verde

Marine Cuau, Nicole E. Avalon, Byeol Ryu…·William H. Gerwick

The paper identifies three new cyclic depsipeptides from a marine cyanobacterium using AI tools and metabolomics, showing their antiplasmodial activity and structural diversity.

DOI 10.1021/acs.jnatprod.6c00391

metabolomicsdeep learning

𝕏 PostBluesky