Caroline A. Spike

The paper identifies a uORF in the lin-41 5'UTR that modulates Let-7 microRNA regulation of lin-41 translation in C. elegans.

The paper identifies SPN-4 as a specificity factor for CCR4-NOT-dependent clearance of maternal mRNAs in C. elegans embryos, showing its role in targeting specific transcripts for decay.

The paper shows that ETC-1 promotes proteasome processivity to degrade oocyte regulatory proteins during the oocyte-to-embryo transition in C. elegans.

This study investigates the role of DDX41 mutations in myelodysplastic syndromes using C. elegans SACY-1, revealing antimorphic activity and transcriptome changes through splicing-dependent and -independent mechanisms.

The paper investigates how LIN-41 is degraded during meiotic maturation in C. elegans, identifying degradation domains and ubiquitin ligase involvement.