Author

Thangavel Samikkannu

Texas A&M Health Science CenterORCID 0000-0001-5071-056XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:ATAC-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:rat· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Arpan AcharyaiD· 1 shared James J. CaiiD· 1 shared Karthick ChennakesavaniD· 1 shared Malaroviyam Samikkannu· 1 shared Shreyan GuptaiD· 1 shared Siddappa N. ByrareddyiD· 1 shared Tayo Israel Olasunkanmi· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Arpan AcharyaORCID

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1 paper

Recent·Most cited

NeurosciencebioRxivPreprintJan 2, 2026

STAT1-Mediated Regulation of IL-17A/CEBPB/NF-κB Axisin HIV-1 Infected Human Cerebral Organoids RevealsTherapeutic Targets for Neuroprotection

Karthick Chennakesavan, Malaroviyam Samikkannu, Shreyan Gupta…·Thangavel Samikkannu

The paper identifies IL-17A, STAT1, CEBPB, and cGAS-STING as key drivers of HIV-associated neuroinflammation using HIV-infected cerebral organoids and validates findings in a primate model.

DOI 10.64898/2025.12.30.697044

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