Author

Karthick Chennakesavan

Texas A&M Health Science CenterORCID 0000-0003-3538-2646Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:ATAC-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Organism:rat· 1

Frequent Co-Authors

Alyssa EalyiD· 1 shared Anil KumariD· 1 shared Anumantha G. KanthasamyiD· 1 shared Arpan AcharyaiD· 1 shared Arthi KanthasamyiD· 1 shared Bharathi N. Palanisamy· 1 shared Chelva Janarthanam· 1 shared Emir MaloviciD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperNeuroscience

Alyssa EalyORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintJan 2, 2026

STAT1-Mediated Regulation of IL-17A/CEBPB/NF-κB Axisin HIV-1 Infected Human Cerebral Organoids RevealsTherapeutic Targets for Neuroprotection

Karthick Chennakesavan, Malaroviyam Samikkannu, Shreyan Gupta…·Thangavel Samikkannu

The paper identifies IL-17A, STAT1, CEBPB, and cGAS-STING as key drivers of HIV-associated neuroinflammation using HIV-infected cerebral organoids and validates findings in a primate model.

DOI 10.64898/2025.12.30.697044

humanrat

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NeurosciencebioRxivPreprintMar 18, 2025

KCa3.1 Contributes to Neuroinflammation and Nigral Dopaminergic Neurodegeneration in Experimental models of Parkinson's Disease

Manikandan Samidurai, Karthick Chennakesavan, Souvarish Sarkar…·Arthi Kanthasamy

This study shows that inhibiting KCa3.1 channels reduces neuroinflammation and dopaminergic neurodegeneration in Parkinson's disease models.

1 citation

mouseexperimental assay

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