Longhui Qiu

The paper shows that NPFF neurons in the caudal brainstem control gastric emptying and intestinal transit by responding to duodenal nutrient sensing.

This study demonstrates that in vivo delivery of genome editing enzymes can be amplified through cell-to-cell transfer, significantly increasing editing efficiency in mice.

This study shows that GPCR-Ga13 signaling is essential for intestinal IEL survival by enabling migration to cytokine-rich niches, with loss of G13 leading to impaired function and increased disease severity.

The paper identifies two distinct CGRP neuron populations with different roles in post-ingestive learning, showing one is involved in learning about post-ingestive effects while not affecting food consumption.

This study shows that the local lung environment, not the peripheral environment, drives phenotypic diversity in monocyte-derived lung cells during Mtb infection.

The paper identifies distinct AP neuron subtypes that respond to different macronutrients and physiological signals, revealing their roles in satiety and homeostasis beyond nausea.

This paper develops a method to selectively kill cancer cells with TP53 mutations by using RNA-guided Cas12a2 to induce chromatin shredding through targeting cancer-specific transcripts.

The paper shows that mite-induced migratory CD103+ skin ILC2s enter the lung, become resident, and alter lung immunity by changing immune response trajectories.

This study identifies GPT2-dependent alanine catabolism as a metabolic vulnerability in MYC-driven liver cancer, showing that inhibiting GPT2 reduces tumor growth in mouse models.

The paper investigates how food ingestion is encoded in the caudal nucleus of the solitary tract (cNTS) by comparing neural activity during gastric and oral food delivery in behaving animals.

This paper develops a technique for intravital imaging of pulmonary lymphatics in mice, revealing ventilation-dependent and -independent lymph flow and leukocyte migration during inflammation and cancer metastasis.

This paper identifies a dopamine pathway that enables flavour-nutrient learning by integrating interoceptive signals from the mouth and gut.

This study shows that loss of neutrophil Shp1 causes severe lung injury and death in mice, and that activating Shp1 can reduce inflammation and lung damage.