Molecular BiologyProceedings of the National Academy of SciencesPeer-reviewed
PTP1B inhibition promotes microglial phagocytosis in Alzheimer's disease models by enhancing SYK signaling
Yuxin Cen, Steven R. Alves, Dongyan Song…·Nicholas K. Tonks
This study shows that inhibiting PTP1B enhances microglial phagocytosis and reduces Aβ burden in AD models by boosting SYK signaling.
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